![]() Exercise Capacity and Functional Performance in Heart Failure Patients Supported by a Left Ventricular Assist Device at Discharge From Inpatient Rehabilitation. Schmidt T., Bjarnason-Wehrens B., Bartsch P., Deniz E., Schmitto J., Schulte-Eistrup S., Willemsen D., Reiss N. LVAD Pump Flow Does Not Adequately Increase With Exercise. Gross C., Marko C., Mikl J., Altenberger J., Schlöglhofer T., Schima H., Zimpfer D., Moscato F. Higher V D/V T as a surrogate for RV-PA uncoupling could be another marker of persistent exercise limitations in LVAD patients. ![]() (4) Conclusions: LVAD patients displayed higher V D/V T compared to HFrEF. As a secondary outcome CPET variables were evaluated for a composite of hospitalization due to worsening heart failure and overall mortality over 22 months. ![]() As a primary outcome NTproBNP, CPET, and echocardiographic variables were analyzed for their potential to discriminate between HFrEF and LVAD. (2) Methods: We investigated 197 patients with heart failure and reduced ejection fraction with ( n = 89) and without (HFrEF, n = 108) LVAD. Higher dead space ventilation (V D/V T) may be a surrogate for right ventricular to pulmonary artery uncoupling (RV-PA) during cardiopulmonary exercise testing (CPET) to explain persistent exercise limitations. (1) Background: The exercise capacity of patients with a left ventricular assist device (LVAD) remains limited despite mechanical support.
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